Predicting Type 2 Diabetes Incidence with Genome-wide Gene-gene and Gene-diet Interactions (OR31-08-19)
نویسندگان
چکیده
منابع مشابه
Gene-Environment and Gene-Treatment Interactions in Type 2 Diabetes
Type 2 diabetes has rapidly emerged as a global health crisis. Because population-level genetic changes take many generations to occur, this epidemic is almost certainly primarily a consequence of recent environmental changes; nonetheless, diabetes does appear to occur preferentially in genetically predisposed populations, which suggests that the effects of pre-existing susceptibility genes hav...
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Genome-wide association studies (GWAS) have successfully identified a number of single-nucleotide polymorphisms (SNPs) associated with colorectal cancer (CRC) risk. However, these susceptibility loci known today explain only a small fraction of the genetic risk. Gene-gene interaction (GxG) is considered to be one source of the missing heritability. To address this, we performed a genome-wide se...
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Introduction: Type 2 diabetes is a common multifactorial disease. Studies have shown that the NLRP3 gene plays an important role in insulin resistance. The aim of this study was to investigate the association of rs4612666 polymorphisms of NLRp3 gene with type 2 diabetes in the population of East Azarbaijan province. Methods: In this case-control study, blood samples from 110 patients and 110 h...
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ژورنال
عنوان ژورنال: Current Developments in Nutrition
سال: 2019
ISSN: 2475-2991
DOI: 10.1093/cdn/nzz037.or31-08-19